STUDY OF THE CONDITION OF THE ORAL MUCOSA OF RATS WITH LONG-TERM ADMINISTRATION OF NIFEDIPINE

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Название журнала: Восточно Европейский Научный Журнал, Выпуск: , Том: , Страницы в выпуске: -
Автор: Savelieva N.N. doctor of medical sciences, associate professor, Department of Dentistry Kharkiv National Medical University Schneider S.A. doctor of medical sciences, professor director of the SE “Institute of Dentistry and Maxillofacial Surgery of the National Academy of Medical Sciences of Ukraine” Tkachenko E.K. сandidate of biological sciences, head of the experimental pathology Sector of the SE “Institute of Dentistry and Maxillofacial Surgery of the National Academy of Medical Sciences of Ukraine” Nikolaenko K.V. laboratory assistant of the experimental pathology Sector of the SE “Institute of Dentistry and Maxillofacial Surgery of the National Academy of Medical Sciences of Ukraine”
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Анотация: Abstract. The article examines the effect of long-term oral nifedipine on biochemical and cytomorphological changes in the oral mucosa of rats. 1 group intact (5 individuals). The 2nd group (7) received per os nifedipine in a dose of 5 mg / kg body weight of rats for 70 days. Nifedipine in the oral mucosa caused an increase in peroxida- tion processes, inadequate functioning of antioxidant enzymes, an increase in the activity of the pro-inflammatory enzyme - acid phosphatase. According to morphometric studies revealed violations in the epithelial layer and the lamina propria of the oral mucosa.
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Данные для цитирования: Savelieva N.N. doctor of medical sciences, associate professor, Department of Dentistry Kharkiv National Medical University Schneider S.A. doctor of medical sciences, professor director of the SE “Institute of Dentistry and Maxillofacial Surgery of the National Academy of Medical Sciences of Ukraine” Tkachenko E.K. сandidate of biological sciences, head of the experimental pathology Sector of the SE “Institute of Dentistry and Maxillofacial Surgery of the National Academy of Medical Sciences of Ukraine” Nikolaenko K.V. laboratory assistant of the experimental pathology Sector of the SE “Institute of Dentistry and Maxillofacial Surgery of the National Academy of Medical Sciences of Ukraine” . STUDY OF THE CONDITION OF THE ORAL MUCOSA OF RATS WITH LONG-TERM ADMINISTRATION OF NIFEDIPINE. Восточно Европейский Научный Журнал. Биологические науки. ; ():-.



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