Список авторов:

Kolesnyk Mykhaylo MD, PhD, DSci, Professor of Department of Family Medicine, Therapy, Cardiology and Neurology, Faculty of Postgraduate Education, Zaporizhzhia State Medical University Sokolova Maryna MD, Post-Graduate Student of Department of Family Medicine, Therapy, Cardiology and Neurology, Faculty of Postgraduate Education, Zaporizhzhia State Medical University


Abstract. Background and Objectives: Evaluation of diastolic function (DF) of left ventricle (LV) provides
an important prognostic information in many cardiovascular diseases. The existing algorithms for its diagnosis do
not always permit to identify its deterioration. The aim of our study was to assess the longitudinal strain of the left
atrium (LA) in postmenopausal women with arterial hypertension (AH) and different variants of DF; Materials
and Methods: The study involved 100 postmenopausal hypertensive women (mean age – 57.8 ± 4.3 years). All
patients underwent general clinical examination, standard transthoracic and speckle tracking echocardiography.
Diagnostics of diastolic dysfunction (DD) of the LV was performed in accordance with the 2009 year recommen-
dations of the American and European society of echocardiography. All patients were divided into three groups
depending on the state of DF LV: the 1 st group included 31 women with normal DF LV, the 2 nd group consisted
of 38 patients with indetermined result, and 31 individuals of the 3 rd group had LV DD. Results: Women with DD
LV had higher values of LAVI and LV mass index. Abnormal values of e’ sept, e’ lat and E/e’ were found in
patients with indetermined DF and with DD. Impairment of the reservoir phase of LA function was associated
with the presence of DD LV. Subjects with any LV DF except normal had lower values of LA deformation
(p<0,05). Reduction of LA GLS in women with AH and abnormal DF LV was detected only with the use of R-
synchronization of ECG. Е/е`/GLS LA was increased as far as breaking DF LV with its maximum value in women
with DD LV. Conclusion: Left atrial strain can be used to assess left ventricular diastolic function and differentiate
its normal state and varying degrees of diastolic dysfunction in postmenopausal women with AH.

Ключевые слова:

Keywords: diastolic dysfunction, arterial hypertension, postmenopausal women, speckle tracking echocardi- ography, left atrium strain View Fullscreen


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