FEATURES OF THE INTERCONNECTION OF TRADITIONAL RISK FACTORS WITH THE ACTIVITY OF THE INFLAMMATORY PROCESS AND ATHEROSCLEROSIS IN PATIENTS WITH PSORIATIC ARTHRITIS (18-23)

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Дата публикации статьи в журнале: 2019/09/19
Название журнала: Восточно Европейский Научный Журнал, Выпуск: 48, Том: 3, Страницы в выпуске: 18-23
Автор: Khimion L.V.
Kyiv , Shupyk National Medical Academy of Postgraduate Education,
Автор: Boiko A.V.
Kyiv , Shupyk National Medical Academy of Postgraduate Education,
Анотация: The study of the connection of psoriasis and cardiovascular diseases is paid much attention by domestic and foreign scientists. The article is devoted to the study of the relationship of traditional risk factors (RF) for cardiovascular diseases (CVD) with the activity of the inflammatory process and atherosclerosis in patients with psoriatic arthritis (PsA). The study included 42 patients with PsA who did not have atherosclerotic CVD, diabetes, chronic kidney disease and other serious diseases, did not take statins, the control group consisted of 20 patients with psoriasis (PS) and 20 practically healthy individuals who had no signs of rheumatic, infectious and other inflammatory diseases were screened. It was revealed that in patients with PsA, the severity of the atherosclerotic process is more compared with patients with PS (the RF profiles were the same). The highest levels of C-reactive protein, fibrinogen, uric acid, intima-media complex thickness, atherosclerotic plaque frequency were found in patients in the PsA group, which may indicate a pathogenetic association of additional RF with the development of a more common atherosclerotic process.
Ключевые слова: psoriatic arthritis   psoriasis   cardiovascular diseases   dyslipidemia   atherosclerosis   C-reactive protein   uric acid   uric acid  
Данные для цитирования: Khimion L.V., Boiko A.V. , . FEATURES OF THE INTERCONNECTION OF TRADITIONAL RISK FACTORS WITH THE ACTIVITY OF THE INFLAMMATORY PROCESS AND ATHEROSCLEROSIS IN PATIENTS WITH PSORIATIC ARTHRITIS (18-23). Восточно Европейский Научный Журнал. Медицинские науки. 2019/09/19; 48(3):18-23.

Список литературы: 1. Badokin, V. V. Terapevticheskaya aktivnost' i bezopasnost' artrofoona pri psoriaticheskom artrite / V. V. Badokin, Yu. L. Korsakova // Consilium Medicum [E'lektronny'j resurs]. – 2006. – № 8. – Rezhim dostupa: http://con-med.ru/magazines/ consilium_medicum/212569/212305/. – Data dostupa: 27.03.2014. 2. Cytokine profiles during infliximab monotherapy in psoriatic arthritis / A. Mastroianni [at al.] // British Journal of Dermatology. – 2005. – Vol. 153, № 3. – P. 531–536. 3. Gottlieb, A. B. Psoriasis comorbidities / A. B. Gottlieb, C. Chao, F. Dann // Journal of Dermatological Treatment. – 2008. – Vol. 19, № 1. – R. 5–21. 4. Milosavljevic, J. Ultrasound and Power Doppler Evaluation of the Hand and Wrist in Patients with Psoriatic Arthritis / J. Milosavljevic, U. Lindqvist, A. Elvin // Acta Radiologica. – 2005. – Vol. 46, № 4. – P. 374–385. 5. Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 2. Psoriatic arthritis: overview and guidelines of care for treatment with an emphasis on the biologics / A. Gottlieb [at al.] // Journal of the American Academy of Dermatology. – 2008. – Vol. 58, № 5. – P. 851– 864. 6. Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 2. Psoriatic arthritis: overview and guidelines of care for treatment with an emphasis on the biologics / A. Gottlieb [at al.] // Journal of the American Academy of Dermatology. – 2008. – Vol. 58, № 5. – P. 851– 864. 7. Effects of alefacept on health-related quality of life in patients with psoriasis results from a randomized, placebo-controlled phase II trial / C. N. Ellis [at al.] // American Journal of Clinical Dermatology. – 2003. – Vol.4, №2. – P. 131–139. 8. Stefano, I. Echographic test and cyclosporin therapy in psoriatic arthritis / I. Stefano, R. Eugenio, R. Antonio // Journal of the European Academy of Dermatology and Venereology. – 2000. – Vol. 14, № 3. – P. 232–233. 9. Kochergin, N. G. Itogi raboty' Pervoj vsemirnoj konferencii po psoriazu i psoriaticheskomu artritu / N. G. Kochergin, S. N. Kochergin, L. M. Smirnova // Russkij medicinskij zhurnal [E'lektronny'j resurs]. – 2006. – Rezhim dostupa: http://www.rmj.ru/articles_4306.htm. – Data dostupa: 03.04.2014. 10. Psoriasis and diabetes: a population-based cross-sectional study / A. D. Cohen [at al.] // Journal of the European Academy of Dermatology and Venereology. – 2008. – Vol. 22, № 5. – R. 585–589. 11. Titov V. N. Vzaimosvyaz mochevoy kisloty s pokazatelyamya lipidnogo obmena u lits s nizkim i srednim riskom po shkale SCORE / V. N. Titov. S. A. Boytsov. S. F. Urazalina i soavt. // Ateroskleroz i dislipidemii. – 2013. – №2. – S. 31-39 12. Chandran, V. Sensitivity and specificity of the caspar criteria for psoriatic arthritis in a family medicine clinic setting / V. Chandran, C. T. Schentag, D. D. Gladman // The Journal of Rheumatology. – 2008. – Vol. 35, № 10. – P. 2069–2070. 13. Mіtchenko O.І.. Lutay M.І. Dislіpіdemії: dіagnostika. profіlaktika ta lіkuvannya. Metodichnі rekomendatsії asotsіatsії kardіologіv Ukraїni. – K.: Morіon. 2011. 14. Kovalenko V.M Vpliv іmunnogo statusu і lіpіdnikh faktorіv na progresuvannya subklіnіchnogo aterosklerozu і rozvitok sertsevo-sudinnikh zakhvoryuvan u patsієntіv іz revmatoїdnim artritom // Kovalenko V.M., L.V. Khimion, G.І. Lysenko, O.O. Garmisch / Ukr. tevmatol. Zhurn. – 2011. 15. Gonzalez-Juanatey C., Llorca J., Amigo-Diaz E. [et al.] High prevalence of subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease or classic atherosclerosis risk factors. // Arthritis Rheum. – 2007 - 57(6) – Р. 1074-1080. 16. Franse LV. Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP) / Franse LV, Pahor M, Di Bari M et al. // J. Hypertens. – 2000. – Vol.18. – P.1149-1154. 17. Grayson PC. Hyperuricemia and incident hypertension: a systematic review and meta-analysis. / Grayson PC, Kim SY, LaValley M et al. // Arthritis Care Res (Hoboken). – 2011. – Vol.63(1). – Р.102-110. 18. Keenan T. Relation of uric acid to serum levels of high-sensitivity C-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis. / Keenan T, Blaha MJ, Nasir K et al. // Am J Cardiol. – 2012. – Vol.110(12). – P.1787-1792.